K. Ueno, J. Morstein, K. Ofusa, S. Naganos, E. Suzuki-Sawano, S. Minegishi, S. P. Rezgui, H. Kitagishi, B. W. Michel, C. J. Chang, J. Horiuchi, M. Saitoe
“Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamin Release”
Journal of Neuroscience, 40, 3533–3548 (2020).
(DOI: 10.1523/JNEUROSCI.2378-19.2020)
論文発表
2023年
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A. T. Kawaguchi, T. Tanaka, M. Yamano, H. Sumiyoshi, H. Kitagishi, Y. Yamada, G. T. Kawaguchi, J. Bergsland
“Carboxyhemoglobin Particle Infusion, but not Carbon Monoxide Inhalation ameliorates Myocardial Infarction via Attenuated Oxidative Stress and In Situ Inflammation in a Rat Model”
Medical Research Archives, 11, 11 (2023).
(DOI: https://doi.org/10.18103/mra.v11i11.4810 ) -
M. Noguchi, Q. Mao, A. Nakagami, H. Kitagishi
“Spontaneous reduction of iron(iii)porphyrin to iron(ii)porphyrin–CO complex in mouse circulation”
Chemical Communications, 59, 6211–6214 (2023).
https://pubs.rsc.org/en/content/articlelanding/2023/cc/d3cc00420a -
S. Mohan, L.-A. Barel, D. E. Benrahla, B. Do, Q. Mao, H. Kitagishi, M. Rivard, R. Motterlini, R. Foresti
“Development of carbon monoxide-releasing molecules conjugated to polysaccharides (glyco-CORMs) for delivering CO during obesity”
Pharmacological Research, 191, 106770 (2023).
(DOI: https://doi.org/10.1016/j.phrs.2023.106770) -
Q. Mao, H. Kitagishi
“Inclusion Complex Formation with Tetra-PEGylated Tetraphenylporphyrin and Face-to-Face Cyclodextrin Dimer through Unprecedented Molecular Threading”
Chemistry–A European Journal, e202300408 (2023).
(DOI: https://doi.org/10.1002/chem.202300408) -
Q. Mao, X. Zhao, A. Kiriyama, S. Negi, Y. Fukuda, H. Yoshioka, A. T. Kawaguchi, R. Motterlini, R. Foresti, H. Kitagishi
“A synthetic porphyrin as an effective dual antidote against carbon monoxide and cyanide poisoning”
Proceedings of the National Academy of Sciences, 120, e2209924120 (2023).
(DOI: 10.1073/pnas.2209924120 ) -
S. Negi, M. Hamori, Y. Kawahara-Nakagawa, M. Mashimo, M. Imanishi, N. Kuki, Y. Kawahito, T. Manabe, N. Kawamura, J. Yasukawa, H. Kitagishi, Y. Sugiura
“Effect of Charged-cluster Distribution of the ZIF268 Zinc Finger Surface on Cell Membrane Permeability”
Chemistry Letters, 52, 75–78 (2023).
(DOI: https://doi.org/10.1246/cl.220464) -
S. Negi, M. Hamori, Y. Kubo, H. Kitagishi, K. Kano
“Monolayer formation and chiral recognition of binaphthyl amphiphiles at the air–water interface”
Bulletin of the Chemical Society of Japan, 96, 48–56 (2023).
(DOI: 10.1246/bcsj.20220286) -
S. Negi, M. Hamori, H. Kitagishi, K. Kano
“Highly Ordered Monolayers of an Optically Active Amphiphilic Pyrene Derivative at the Air–Water Interface”
Bulletin of the Chemical Society of Japan, 95, 1537–1545 (2022).
(DOI: 10.1246/bcsj.20220233) -
M. Tang, Y.-H. Liu, H. Liu, Q. Mao, Q. Yu, H. Kitagishi, Y.-M. Zhang, L. Xiao, Yu Liu
“Supramolecular Dual Polypeptides Induced Tubulin Aggregation for Synergistic Cancer Theranostics”
Journal of Medicinal Chemistry, 65, 13473-13481 (2022).
(DOI: 10.1021/acs.jmedchem.2c01398) -
H. Kitagishi, I. Sagami
“Role of CO in Circadian Clock”
In Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential, (Chapter 5, pp 97–107, 2022).
(DOI: https://doi.org/10.1002/9781119783435.ch5) -
S. Negi, M. Hamori, A. Sato, K. Shimizu, Y. Kawahara-Nakagawa, T. Manabe, N. Shibata, H. Kitagishi, M. Mashimo, Y. Sugiura
“Transpeptidation Reaction Mediated by Ligand- and Metal Cofactor-Substituted Sortase A from Staphylococcus aureus”
Bulletin of the Chemical Society of Japan, 95, 1025–1031 (2022).
(DOI: 10.1246/bcsj.20220098) -
S. Negi, M. Hamori, Y. Kawahara-Nakagawa, M. Imanishi, M. Kurehara, C. Kitada, Y. Kawahito, K. Kishi, T. Manabe, N. Kawamura, H. Kitagishi, M. Mashimo, N. Shibata, Y. Sugiura
“Importance of two-dimensional cation clusters induced by protein folding in intrinsic intracellular membrane permeability”
RSC Chemical Biology, 3, 1076–1084 (2022).
https://pubs.rsc.org/en/content/articlehtml/2022/cb/d2cb00098a -
R. Tachikawa, H. Saito, H. Moteki, M. Kimura, H. Kitagishi, F. Arce Jr., G. L. See, T. Tanikawa, Y. Inoue
“Preparation, Characterization, and In Vitro Evaluation of Inclusion Complexes Formed between S-Allylcycteine and Cyclodextrin”
ACS Omega, 7, 31233–31245 (2022).
(DOI: 10.1021/acsomega.2c03489) -
T. Nagasaki, H. Maeda, K. Taguchi, H. Yanagisawa, K. Nishida, K. Kobayashi, N. Wada, I.Noguchi, R. Murata, H. Sakai, H. Kitagishi,J. Saruwatari, H. Watanabe,M. Otagiri, T. Maruyama
“A Bioinspired Carbon Monoxide Delivery System Prevents Acute Kidney Injury and the Progression to Chronic Kidney Disease”
Redox Biology, 54, 102371 (16 pages) (2022).
(DOI: 10.1016/j.redox.2022.102371) -
H. Kitagishi, Q. Mao
“Capture of carbon monoxide using a heme protein model: from biomimetic chemistry of heme proteins to physiological and therapeutic applications”
Polymer Journal, 54, 465-472 (2022).
(DOI: 10.1038/s41428-021-00591-y) -
A. Nakagami, Q. Mao, G. Gouhier, H. Arima, H. Kitagishi
“FRET-Based In-Cell Detection of Highly Selective Supramolecular Complexes of meso-Tetraarylporphyrin with Peptide/BODIPY-modified Per-O-methyl-β-cyclodextrins”
ChemBioChem, 16, 3190-3198 (2021)..
(DOI: 10.1002/cbic.202100380) -
Q. Mao, P. K. Das, S. Le Gac, B. Boitrel, V. Dorcet, K. Oohora, T. Hayashi, H. Kitagishi
“Functional Myoglobin Model Composed of a Strapped Porphyrin/Cyclodextrin Supramolecular Complex with an Overhanging COOH That Increases O2/CO Binding Selectivity in Aqueous Solution”
Inorganic Chemistry, 60, 12392–12404 (2021)..
(DOI: 10.1021/acs.inorgchem.1c01628) -
Q. Mao, A. T. Kawaguchi, S. Mizobata, R. Motterlini, R. Foresti, H. Kitagishi
“Sensitive quantification of carbon monoxide (CO) in vivo reveals a protective role of circulating hemoglobin in CO intoxication”
Communications Biology, 4, 425 (2021) (15 pages).
https://www.nature.com/articles/s42003-021-01880-1 -
H. Kitagishi, K. Kano
“Synthetic heme protein models that function in aqueous solution”
Chemical Communications, 57, 148–173 (2021)..
(DOI: 10.1039/D0CC07044K) -
H. Kitagishi, M. Jiromaru, N. Hasegawa
“Intracellular Delivery of Adamantane-tagged Small Molecule, Proteins, and Liposomes Using an Octaarginine-conjugated β-Cyclodextrin”
ACS Applied Bio Materials, 3, 4902–4911 (2020).
(DOI: 10.1021/acsabm.0c00421) -
-
R. Nishiyabu, Y. Takahashi, T. Yabuki, S. Gommori, Y. Yamamoto, H. Kitagishi, Y. Kubo
“Boronate Sol-Gel Method for One-Step Fabrication of Polyvinyl Alcohol Hydrogel Coating by Simple Cast- and Dip-Coating Techniques”
RSC Advances, 10, 86–94 (2020).
(DOI: 10.1039/C9RA08208E) -
M. Vonesch, J. A. Wytko, H. Kitagishi, K. Kano, J. Weiss
“Modeling Haemoproteins: Porphyrins and Cyclodextrins as Sources of Inspiration”
Chemical Communications, 27, 44–52 (2019).
(DOI: 10.1039/C9CC07545C) -
H. Kitagishi
“In Vivo Reactions Triggered by Selective Removal of Endogenous Carbon Monoxide in Blood Using an Artificial Hemoprotein Model Complex”
Artificial Blood, 27, 44–52 (2019) (written in Japanese).
(https://www.blood-sub.jp/kaisinituite.php) -
H. Kitagishi, M. Saito, Q. Mao, A. Kiriyama, S. Negi, K. Kano
“Supramolecular Complexation in Biological Media: NMR Study on Inclusion of an Anionic Tetraarylporphyrin into a Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin Cavity in Serum, Blood, and Urine”
Chemistry–An Asian Journal, 14, 3320–3328 (2019).
(DOI:10.1002/asia.20190983) -
H. Kitagishi, K. Ohara, D. Shimoji, M. Vonesch, J. Weiss, J. A. Wytko
“Hydrogen Bond Directed Molecular Recognition in Water in a Strapped-Porphyrin-Cyclodextrin Assembly”
Journal of Porphyrins and Phthalocyanines, 23, 569–574 (2019).
(DOI:10.1142/S1088424619500494)R. Suzuki, Y. Inoue, I. Murata, H. Nomura, Y. Issiki, M. Hashimoto, Y. Kudo, H. Kitagishi, S. Kondo, I. Kanamoto
“Preparation, Characterization, and Study of the Antimicrobial Activity of a Hinokitiol-copper(II)/γ-cyclodextrin Ternary Complex”
Journal of Molecular Structure, 1194, 9–27 (2019).
(DOI:10.1016/j.molstruc.2019.05.078)M. Kodera, Y. Kadoya, K. Aso, K. Fukui, A. Nomura, Y. Hitomi, H. Kitagishi
“Acceleration of Hydrolytic DNA Cleavage by Dicopper(II) Complexes with p-Cresol-Derived Dinulearing Ligands at Slightly Acidic pH and Mechanistic Insights”
Bulletin of the Chemical Society of Japan, 92, 739–747 (2019).
(DOI:10.1246/bcsj.20180353)A. Ollivier, R. Foresti, Z. El Ali, T. Martens, H. Kitagishi, R. Motterlini, M. Rivard
“Design and Biological Evaluation of Manganese- and Ruthenium-based Hybrid CO-RMs (HYCOs)”
ChemMedChem, 14, 1684–1691 (2019).
(DOI:10.1002/cmdc.201900426)K. Oohora, R. Kajihara, M. Jiromaru, H. Kitagishi, T. Hayashi
“Arginine Residues Provide a Multivalent Effect for Cellular Uptake of a Hemoprotein Assembly”
Chemistry Letters, 48, 295–298 (2019).
(DOI:10.1246/cl.180897)Q. Mao, H. Kitagishi
“Optimized Synthesis of a Per-O-methylated β-Cyclodextrin Dimer Linked at the Secondary Face by a Pyridine Ligand”
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 93, 67–76 (2019).
(DOI:10.1007/s10847-018-0839-4)2018年
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L. Braud, M. Pini, L. Muchova, S. Manin, H. Kitagishi, D. Sawaki, G. Czibik, J. Ternacle, G. Derumeaux, R. Foresti, R. Motterlini
“Carbon Monoxide-induced Metabolic Switch in Adipocytes Improves Insulin Resistance in Obese Mice”
JCI Insight, 3, e123485 (2018).
(DOI:10.1172/jci.insight.123485) -
A. T. Kawaguchi, A. Salybekov, M. Yamano, H. Kitagishi, K. Sekine
“PEGylated Carboxyhemoglobin Bovine (SANGUINATE) Ameliorates Myocardial Infarction in a Rat Model”
Artificial Organs, 42, 1174–1184 (2018).
(DOI:10.1111/aor.13384) -
S. Minegishi, I. Sagami, S. Negi, K. Kano, H. Kitagishi
“Circadian Clock Disruption by Selective Removal of Endogenous Carbon Monoxide”
Scientific Reports, 8, 11996 (2018).
(DOI: 10.1038/s41598-018-30425-6) -
H. Kitagishi, D. Shimoji, T. Ohta, R. Kamiya, Y. Kudo,
A. Onoda, T. Hayashi, J. Weiss, J. A. Wytko, K. Kano“A Water-Soluble Supramolecular Complex that Mimics the Heme/Copper Hetero-Binuclear Site of Cytochrome c Oxidase”
Chemical Science, 9, 1989–1995 (2018).
(DOI: 10.1039/c7sc04732k)
2017年
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S. Minegishi, A. Yumura, H. Miyoshi, S. Negi, S. Taketani,
R. Motterlini, R. Foresti, K. Kano, H. Kitagishi
“Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-permeable Hemoprotein-model Complexes”
Journal of the American Chemical Society, 139, 5984–5991 (2017).
(DOI: 10.1021/jacs.7b02229) -
H. Kitagishi, S. Minegishi
“Iron(II)porphyrin–Cyclodextrin Supramolecular Complex as a Carbon Monoxide-Depleting Agent in Living Organisms”
Chemical and Pharmaceutical Bulletin, 65, 336–340 (2017).
(DOI: 10.1248/cpb.c16-00767) -
H. Kitagishi, Y. Sugaya, K. Komazawa, M. Tamaki, K. Kano
“Participation of Hydroxyl Radical in the Formation of Verdoheme-type Compound in the Reaction of a Ferric Porphyrin with Hydrogen Peroxide”
Chemistry Letters, 46, 509–512 (2017).
(DOI: 10.1246/cl.161161) -
H. Kitagishi, Q. Mao, N. Kitamura, T. Kita
“HemoCD as a Totally Synthetic Artificial Oxygen Carrier: Improvements in the Synthesis and O2/CO Discrimination”
Artificial Organs, 41, 372–380 (2017).
(DOI: 10.1111/aor.12870) -
R. Nishiyabu, S. Iizuka, S. Minegishi, H. Kitagishi, Y. Kubo
“Surface Modification of a Polyvinyl Alcohol Sponge with Functionalized Boronic Acids to Develop Porous Materials for Multicolor Emission, Chemical Sensing and 3D Cell Culture”
Chemical Communications, 53, 3563–3566 (2017).
(DOI: 10.1039/c7cc00490g)
2016年
-
H. Kitagishi, S. Kurosawa, K. Kano
“Intramolecular Oxidative O-Demethylation of an Oxoferryl Porphyrin Complexed with a Per-O-methylated β-Cyclodextrin Dimer”
Chemistry –An Asian Jouranl, 11, 3213–3219 (2016).
(DOI:10.1002/asia.201601097) -
W. Takabe, Y. Urano, D. H. Vo, K. Shibuya, M. Tanno,
H. Kitagishi, T. Fujimoto, N. Noguchi
“Esterification of 24S-OHC Induces Formation of Atypical Lipid Droplet-like Structures, Leading to Neuronal Cell Death.
Journal of Lipid Research, 57, 2005–2014 (2016).
(DOI: 10.1194/jlr.M068775) -
K. Shibuya, T. Watanabe, Y. Urano, W. Takabe, N. Noguchi,
H. Kitagishi
“Synthesis of 24(S)-Hydroxycholesterol Esters Responsible for the Induction of Neuronal Cell Death”
Bioorganic & Medicinal Chemisty, 24, 2559–2566 (2016).
(DOI: 10.1016/j.bmc.2016.04.024) -
H. Kitagishi, S. Minegishi, A. Yumura, S. Negi, S. Taketani,
Y. Amagase, Y. Mizukawa, T. Urushidani, Y. Sugiura, K. Kano
“Feedback Response to Selective Depletion of Endogenous Carbon Monoxide in the Blood”
Journal of the American Chemical Society, 138, 5417–5425 (2016).
(DOI: 10.1021/jacs.6b02211) -
K. Imabeppu, H. Kuwano, E. Yutani, H. Kitagishi, K. Kano
“Photoinduced Homolysis of Alkyl-Cobalt(III) Bonds in a Cyclodextrin Cage”
European Journal of Inorganic Chemistry, 1784–1789 (2016).
(DOI: 10.1002/ejic.201600208)
2015年
-
H. Kitagishi, H. Kawasaki, K. Kano
“Bioconjugation of Serum Albumin to a Maleimide-appended Porphyrin/Cyclodextrin Supramolecular Complex as an Artificial Oxygen Carrier in the Bloodstream”
Chemistry –An Asian Journal, 10, 1768–1775 (2015).
(DOI: 10.1002/asia.201500451) -
K. Watanabe, T. Suzuki, H. Kitagishi, K. Kano
“Reaction Between a Haemoglobin Model Compound and Hydrosulphide in Aqueous Solution”
Chemical Communications, 51, 4059–4061 (2015).
(DOI: 10.1039/C5CC00057B) -
H. Kitagishi, F. Chai, S. Negi, Y. Sugiura, K. Kano
“Supramolecular Intracellular Delivery of an Anionic Porphyrin by Octaarginine-conjugated Per-O-methyl-β-Cyclodextrin”
Chemical Communications, 51, 2421–2424 (2015).
(DOI: 10.1039/C4CC09042J)
2014年
-
T. Ueda, H. Kitagishi, K. Kano
“Intramolecular Direct Oxygen Transfer from Oxoferryl Porphyrin to a Sulfide Bond”
Inorganic Chemistry, 53, 543–551 (2014).
(DOI: 10.1021/ic4026393) -
H. Kitagishi, K. Minami, K. Kano
“Intracellular Delivery of Anionic meso-Tetraphenylporphyrin – Per-O-methylated β-Cyclodextrin Supramolecular Complex by an Oligoarginine Carrier Peptide”
Chemistry Letters, 43, 1095–1097 (2014).
(DOI: 10.1246/cl.140298)
2013年
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H. Kitagishi, S. Hatada, T. Itakura, Y. Maki, Y. Maeda, K. Kano
“Cellular Uptake of Octaarginine-conjugated Tetraarylporphyin Included by Per-O-methylated β-Cyclodextrin”
Organic & Biomolecular Chemistry, 11, 3203–3211 (2013).
(DOI: 10.1039/c3ob27248f) -
T. Ueda, S. Kumeda, H. Kitagishi, K. Kano
“Intramolecular Oxidative O-Demethylation in a Per-O-methylated β-Cyclodextrin–Iron Porphyrin Inclusion Complex in Aqueous Solution”
Chemistry Letters, 42, 1366–1368 (2013).
(DOI: 10.1246/cl.130678) -
K. Karasugi, H. Kitagishi, K. Kano
“Elongation of Circulation Time of a Diatomic Molecule Receptor in Bloodstream by Attachment to Small Gold Nanoparticles”
Chemistry Letters, 42, 115–117 (2013).
(DOI: 10.1246/cl.2013.115) -
K. Watanabe, H. Kitagishi, K. Kano
“Supramolecular Iron Porphyrin/Cyclodextrin Dimer Complex that Mimics the Functions of Hemoglobin and Methemoglobin”
Angewandte Chemie International Edition, 52, 6894–6897 (2013).
(DOI: 10.1002/anie.201302470)
2012年
-
T. Ueda, H. Kitagishi, K. Kano
“PEGylation of an Artificial O2 and CO Receptor: Synthesis, Characterisation and Pharmacokinetic Study”
Organic & Biomolecular Chemistry, 10, 4337–4347 (2012).
(DOI: 10.1039/c2ob07044h) -
K. Kano, S. Chimoto, M. Tamaki, Y. Itoh, H. Kitagishi
“Supramolecular Dioxygen Receptors Composed of an Anionic Water-soluble Porphinatoiron(II) and Cyclodextrin Dimers”
Dalton Transactions, 41, 453–461 (2012).
(DOI: 10.1039/c1dt11596k) -
H. Kitagishi, K. Kashiwa, K. Kano
“Functionalization of a Protein Surface with Per-O-Methylated β-Cyclodextrin”
Biopolymers, 97, 11–20 (2012).
(DOI: 10.1002/bip.21695) -
K. Karasugi, H. Kitagishi, K. Kano
“Modification of a Dioxygen Carrier, HemoCD, with PEGylated Dendrons for Extension of Circulation Time in the Bloodstream”
Bioconjugate Chemistry, 23, 2365–2376 (2012).
(DOI: 10.1021/bc300303z)
2011年
-
K. Kano, M. Kondo, H. Inoue, H. Kitagishi, B. Colasson, O. Reinaud
“Calorimetric Study on Coordination of Tridentate Imidazolyl Calix[6]arene Ligand to Zinc Ion in Organic Solvents”
Inorganic Chemistry, 50, 6353–6360 (2011).
(DOI: 10.1021/ic200809k) -
K. Kano, T. Ochi, S. Okunaka, Y. Ota, K. Karasugi, T. Ueda, H. Kitagishi
“Preparation and Function of Poly(acrylic acid)s Modified by Supramolecular Complex Composed of Porphinatoiron and a Cyclodextrin Dimer That Bind Diatomic Molecules (O2 and CO) in Aqueous Solution”
Chemistry –An Asian Journal, 6, 2946–2955 (2011).
(DOI: 10.1002/asia.201100354) -
K. Karasugi, H. Kitagishi, K. Kano
“Gold Nanoparticles Carrying Diatomic Molecules (O2 and CO) in Aqueous Solution”
Chemistry –An Asian Journal, 6, 825–833 (2011).
(DOI: 10.1002/asia.201000756) -
K. Watanabe, H. Kitagishi, K. Kano
“Supramolecular Ferric Porphyrins as Cyanide Receptors in Aqueous Solution”
ACS Medicinal Chemistry Letters, 2, 943–947 (2011).
(DOI: 10.1021/ml200231x)
2010年
-
H. Kitagishi, M. Tamaki, T. Ueda, S. Hirota, T. Ohta, Y. Naruta, K. Kano
“Oxoferryl Porphyrin/Hydrogen Peroxide System Whose Behavior is Equivalent to Hydroperoxoferric Porphyrin”
Journal of the American Chemical Society, 132, 16730–16732 (2010)
(DOI: 10.1021/ja106798a) -
H. Kitagishi, S. Negi, A. Kiriyama, A. Honbo, Y. Sugiura, A. T. Kawaguchi, K. Kano
“A Diatomic Molecule Receptor That Removes CO in a Living Organism”
Angewandte Chemie International Edition, 49, 1312–1315 (2010)
(DOI: 10.1002/anie.200906149)
2009年
-
K. Kano, H. Kitagishi
“HemoCD as an Artificial Oxygen Carrier: Oxygen Binding and Autoxidation”
Artificial Organs, 33, 177–182 (2009)
(DOI: 10.1111/j.1525-1594.2008.00704.x)
2008年
-
K. Kano, Y. Itoh, H. Kitagishi, T. Hayashi, S. Hirota
“A Supramolecular Receptor of Diatomic Molecule (O2, CO, NO) in Aqueous Solution”
Journal of the American Chemical Society, 130, 8006–8015 (2008)
(DOI: 10.1021/ja8009583)
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